Research carried out by lab members Marco McSweeney and Dr. Liat Levita, with collaborators Prof. Markus Reuber and Prof. Nigel Hoggard, has recently been published online in Neuroscience Letters.
The research compared 20 brain scans of patients with psychogenic non-epileptic seizures (PNES) and 20 age- and gender-matched controls to investigate group differences in cortical thickness and gyrification patterns, in order to identify possible neurobiological correlates of PNES.
The results showed that, compared to controls, patients with PNES showed increased cortical thickness in motor, sensory and occipital areas, as well as decreased cortical thickness in temporal and frontal brain regions. There were also age-related changes in cortical thickness in the right lateral occipital area in PNES.
These findings partly corroborate, but also differ from previous morphometric studies in PNES, which the authors suggest likely reflect the aetiology and phenomenological heterogeneity of PNES.
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